Food Supplement ImmunVin, Immunity
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Food Supplement Immunvin
Spagyrics. All components are activated by a spagiric method with the addition of vitamins and mineral supplements that are combined to produce a physiological natural agent capable of strengthening the immune system, protecting the body from external aggressions.
The average content of the main ingredients in a daily dose equal to 6 ml, equivalent to 60 drops. The drug should be used to start with small doses.
Composition and description of plant components
hydroalcoholic extract (distilled water, ethyl alcohol, grape juice) Echinacea (Echinacea angustifolia DC): the contents of the root of Echinacea – 20%), dry extract of Maitake mushroom (Grifola frondosa)
Additional components and minerals
trimethylglycine (betaine anhydrous), vitamin B12., Vitamin C, folic acid, vitamin E acetate, zinc gluconate in minor amounts.
How to use
20-30 drops 2 times a day, preferably in the morning and in the first half of the day. Important: spagyrics are highly active anthroposophical preparations. If the doctor has not appointed otherwise, start taking a low-dose: Drops to 5-7 drops.
Shake the bottle before use.
Description of IMMUNVIN
The age-old evolution of nature and ancient wisdom dictate the mode of production ERBENOBILI products.
To use exclusively in the field of occupational health
The nutritional food supplement.
A bottle of 50 ml
The combination of carefully extracted aqueous-alcoholic solution of the alchemical with vitamins and mineral supplements, which are combined to produce a physiological natural agent capable of strengthening the immune system, protecting the body from external aggressions.
Herbal ingredients: water-alcohol extract (distilled water, grape juice (Vitis vinifera L.), wine ethyl alcohol, vegetable of the 20%) of the root of Echinacea (Echinacea angustifolia), dry mushroom extract – a ram (Grifola frondosa) ( Grifola frondosa).
Additional components and mineral supplements: Betaine anhydrous (Trimethyl glycine, or TMG); Vitamin B 12, vitamin C, folate, vitamin E acetate, zinc gluconate in amounts of trace elements.
Activating components of the alchemical methods: alchemical and red wine alcohol.
The recommended dosage is 45 drops a small amount of water, 2 times a day. Before use, we recommend shaking the vial well.
Contraindications: in case of hypersensitivity to one of the components.
have been observed in normal dosages. In case of overdose can be a little confusing gastrointestinal nature. The average number of ingredients contained in a daily dose of 6 ml, which corresponds to 90 drops.
Food Supplement ImmunVin by ERBENOBILI
|Components||At 6 mL|
|The root of Echinacea||1200 mg|
|Trimethylglycine (TMG) (as betaine anhydrous) (from sugar beet)||250 mg|
|The fungus Grifola frondosa (dry extract)||200 mg|
|Vitamin C – 100% of the RDA||80 mg|
|Vitamin E - 100% of the RDA||12 mg|
|Zinc – 15% of the RDA||1.5 mg|
|Folic Acid - 100% of the RDA||200 mg|
|Vitamin In the 12 – 100% of the RDA||2.5 mg|
DESCRIPTION of ACTIVE INGREDIENTS
Echinacea has a good specific immune-stimulating properties, confirmed by experimental tests, such as the ability to increase phagocytosis (the ability to neutralize the bacteria, viruses and foreign bodies) with the help of white blood cells to transform immature white blood cells into mature white blood cells, increase the activity of macrophages and produce as interferon and interleukins, which are substances that are very important for the immune processes.
Numerous clinical studies in patients with influenza syndromes or faringotonzillita were conducted, which showed that the dry extract of Echinacea, taken orally at a dose of 900 mg daily can significantly reduce the intensity of symptoms and disease duration. Studies on children suffering from whooping cough, have shown that Echinacea can reduce the duration of the disease within five days, significantly easing the symptoms. In another study involved a group of patients who were observed clearly reduced number of white blood cells (4350 prior to therapy), and flu-like symptoms. After three days of treatment with dry echinacea extract white blood cell count increased to 5950, and in 55% of patients disappeared symptoms. 45 clinical trials have been conducted to assess the Echinacea efficacy and safety both as prophylactic and therapeutic agents in cases of upper respiratory tract diseases. approximately 4000 patients involved in these studies.
About 20 studies have been devoted to the study of echinacea in the medical aspect, and most of them were found efficiency, superior efficacy to placebo. However, in 4 studies it has shown that this plant is superior to placebo. To evaluate the preventive aspect 25 studies were performed, and their results, on average, may be summarized as follows. In the groups treated with echinacea, the incidence of upper respiratory tract infections was 29.3%, while in the groups treated with placebo, the rate was 36.6%. In addition, subjects who took echinacea recovered significantly more as compared to that observed in the groups receiving placebo.
In another study conducted in rats, studied the question, Can the chronic intake of Echinacea from a young age to old age, increasing longevity and improve the condition of the cells responsible for the immune system, since it is known that such activity of the cells is essential for the survival and longer life. The animals were given daily for 2 mg of extract of Echinacea or placebo throughout their lives, and do not contain bezdietnom power mode.
Prevention and Treatment of Diseases with Homeopathic Methods
After 10 months, we evaluated the survival of animals, which was 79% in the placebo group and 100% in the echinacea group. After 13 months of survival the results were as follows: 46% in the placebo group and 74% in the group. Action Echinacea Echinacea is enhanced by the fungus, called the Grifola frondosa, also known under the name of the fungus-ram. This fungus-ram – very rare type of fungus that grows in northeastern Japan. He showed himself as a drug of great interest, in particular because of the presence of certain substances, such as polysaccharides – glucans. Its immune-stimulating effect due to the ability of these polysaccharides stimulate the activity of macrophages, natural killer cells, cytotoxic T cells, interleuichina-1 (interleukin?), And lymphokines. These properties are documented in an experiment performed on patients with AIDS, Lyme disease and other disorders of the immune system.
Trimethyl glycine betaine anhydrous or extracted from sugar beets, is a strong methylating agent; it plays a particularly important role in the detoxification of homocysteine (a strong oxidant and free radical generator), known as one of the main factors leading to the occurrence of cardiac and vascular diseases. From a structural point of view differs from TMG third DMH presence of a methyl group (CH3), and when released into the gastro-intestinal tract undergoes rapid conversion of it in the liver, providing the same beneficial effects as DMH. Dimethylglycine quite successfully involved in the methylation or trans-methylation – a process in which the methyl groups (CH3) are transferred from one molecule to another. This biochemical process is extremely important for the life, health and regeneration of cells in the body.
Trimethyl glycine is a methylating agent, which, as mentioned above, plays a particularly important role in the detoxification of homocysteine– amino acid, which is present in the blood, methionine. A living organism metabolizes actually only small quantities of homocysteine and it is known that in large quantities it is toxic. You can come to the conclusion that homocysteine is an excellent indicator of the efficiency of biochemical methylation cells. Methionine (product of homocysteine methylation) produces high concentrations of S-adenosyl-methionine (SAM) – natural antidepressant and donor of methyl groups.
Increasing concentrations of SAM is useful for prevention and treatment of certain metabolic disorders, including conditions caused by severe organic deficiency. It is a vital amino acid that has antioxidant activity. It is very important for the functioning of the liver, where it prevents an abnormal accumulation of fat and the production of antibodies. In the presence of vitamin B12, it can be converted to cystine. In combination with inositol and vitamins of group B, it alleviates the symptoms of liver disease, is involved in the formation of carnitine, choline, creatine, adrenaline, etc., and interacts with other substances, detoxifying the harmful compound.
Vitamin C is a natural anti-inflammatory agent, which enhances the body's ability to defend itself against viruses and that it is essential for the proper functioning of cells. In other words, vitamin C acts as an addition to our immune system. He actually plays the main role of an antioxidant, providing a protective effect against free radicals. Zinc is a powerful antioxidant and protects cells from aging. It is present in every cell of the body and is a component of many enzymes (biochemical reactions stimulators) that stimulate the immune system.
Vitamin E (alpha-tocopherol) It is also an important antioxidant. It protects the cell from oxidation, neutralizes free radicals, slowing the aging process, reduces cholesterol, it is shown to enhance the reproductive activity, strengthening sexual function in men, is useful in atherosclerosis, autoimmune diseases, allergies, arthritis, menstrual disorders, menopause and phlebitis .
Vitamin B12 – cyanocobalamin – useful for improving the functioning of the nervous system; it participates in the synthesis of myelin, the formation of red blood cells, ensures the integrity of the nervous system, strengthens the immune system and is involved in the metabolism of carbohydrates, fats and proteins. Name « folate » (Vitamin B9) is derived from the Latin word « folium », which indicates its presence in the leaves of plants such as spinach, are really rich in this vitamin. It is particularly important for the assimilation of proteins, formation of red blood cells, and other cells. Indeed, it is used to generate new cells and genetic material.
Natural Medicine in Belarus
Type: Echinacea angustifolia
Family: Compositae, Asteraceae. Medicinal part: roots.
Echinacea angustifolia, Echinacea pallida, Echinacea purpurea and are plants of the Compositae family, growing in the plains of North America, and used several times to natives and West. Its traditional use has been included in the traditional medicine of the Western States and was later supported by a significant number of studies on this plant. Echinacea contains a large amount of substances with various kinds of activity.
The Quality Score is used most often, it is echinacoside (present in the species angustifolia and pallida, but not purpurea), which is considered responsible for the antioxidant and possibly a bacteriostatic effect. However, of most interest in this plant is its action causing nonspecific stimulation of immune response has been fully demonstrated in the test Carbon clearance, or its activity against phagocytes, which was observed in patients treated with extracts of Echinacea. Through tests it revealed that the mechanism of action is complex, but probably an action provides a mixture of components including alkylamides (responsible for the burnt smell originating from fresh root) and pliatsetileny and polysaccharides. The main types of action Echinacea following:
1. Anti-virus, anti-bacterial and antifungal effect: it is naturally associated with pollen, which has been shown to possess excellent bacteriostatic and antifungal capacity allowing to inhibit bacterial growth, which are difficult to combat, such as Escherichia coli and Pseudomonas aeruginosa.Antivirusnoe action similar to the action of interferon – preventing the penetration of viruses into healthy cells – presumably carried out by the coffee and cichoric acid.
2. Anti-inflammatory effects and wound healing properties: it is certainly in part achieved by the polyamide and polysaccharide fractions. Echinacea also causes an increase in ACTH (kortikotropnogo hormone), and hence increase in the activity of the adrenal cortex with the release of anti-inflammatory steroids. The combination of these properties are manifested in the pronounced anti-inflammatory therapeutic effect.
3. Immunostimulatory effect: at the expense of increasing the number of leukocytes, especially polymorphonuclear granulocytes (or neutrophils) and monocytes – macrophages of the reticuloendothelial system – endotheliae. These cells are used for the absorption of harmful foreign bodies such as bacteria, fungi, etc .. The immunostimulating effect is due to the soluble fraction: Polyhymnius, alkylamido and essential oils, as well as compounds such as polyphenol – Coffee and derivatives, in particular acid cichoric – soluble in water .
The fungus-ram (Maitake)
Type: Grifola frondosa (Dicks) Gray
The family: Polyporaceae. Medicinal part: carpophores.
The local name of Maitake means «dancing mushroom». It is not known, there is a name from its records unit, which at times seem to be «dancing», or from the Chinese tradition associated with the rarity of this type of fungi: the finder it breaks into a dance of joy. Currently, it is grown and produced without any problems, because it is still edible mushroom, although the intensity and quality of its flavor can not be compared with Shiitake.
Among the many components of Grifola, some of which have not yet been identified, allocated D-fraction. It is so effective in stimulating the immune system that the Office of the US Food and Drug Administration (FDA) to include it in the official program of clinical trials Phase II for the treatment of prostate cancer and breast cancer, and degenerative diseases in general, including HIV. D-fraction of the fungus Grifola is a unique polysaccharide complex containing two active molecules at the same time – 1,3-beta-1,6-glucan and beta-glucan – distributed in a large variety and containing a large number of side chains. Apparently, these side chains are able to perform multiple and complex biochemical functions. Their general properties can be summarized as follows: normalization of blood pressure, normalization of glucose metabolism, normalize lipid immunostimulatory effects as a whole.
More specifically – there is a message containing the following experimental facts: prevention and protection of T-cells from the effects of HIV, decisive action in Kaposi's sarcoma, a strong antidiabetic effect, strong antihypertensive effect, a profound effect on blood triglycerides. Special attention deserves auxiliary action that D-fraction can provide for the treatment of tumor with chemotherapy and radiation therapy, avoiding extensive side effects which typically accompany these forms of therapy to decrease the level of pain, hair loss, the onset of nausea, indigestion, etc. it dry ..
The Chinese and the Japanese population used this mushroom for centuries, but only recently opened its remarkable medicinal properties. Its preparation is a strong stimulant of the immune system and is considered to be a valuable and effective tonic and adaptogenic agent useful due to its beneficial effects on the metabolism and the immune system.
TMG (N, N, N – Trimethyl)
Trimethyl glycine extracted from sugar beets, is a strong methylating agent. It plays a particularly important role in the detoxification of homocysteine ??(a strong oxidant and free radical generator), known as one of the main factors leading to the occurrence of cardiac and vascular diseases. Recent studies in the US, has demonstrated the value and efficacy of TMG as a food additive. Its beneficial effects can be shown as follows: a beneficial effect for cardiovascular disease, improves glucose metabolism, improves the absorption of oxygen, reduces chronic fatigue, is an ideal drug in a sporting event, a beneficial effect in diseases of the liver and arthritis.
From a structural point of view differs from TMG third DMH presence of a methyl group (CH3), and when released into the gastro-intestinal tract undergoes rapid conversion of it in the liver, providing the same beneficial effects as DMG, and more. Dimethylglycine quite successfully involved in the methylation or trans-methylation – a process in which the methyl groups (CH3) are transferred from one molecule to another. This biochemical process is extremely important for the life, health and regeneration of cells in the body.
Vitamin B12 (Cyanocobalamin)
Vitamin B12 (Cyanocobalamin) – water-soluble vitamin required for the formation of red blood cells. It is useful for the prevention of anemia, it promotes the formation and longevity of cells. It is also crucial for proper digestion and absorption of food, the synthesis of proteins, as well as for the metabolism of carbohydrates and fats. It is useful for preventing nerve damage, properly maintain the fertility and contributes to hormonal development.
Vitamin C (L-ascorbic acid)
L-ascorbic acid (vitamin C) is a water-soluble vitamin with antioxidant properties that performs multiple functions in the body. With a lack of vitamin C in our body are such things as progressive destructive effects of oxidative stress on the cells of the vessel walls due to the attack of free radicals and/or progressive depletion of collagen in the vessel walls, and their destruction. This occurs under the effect of alpha-lipoprotein, which gradually accumulates, leading to atherosclerosis and subsequently cause a cascade of other dangerous abnormalities.
Vitamin C is a natural anti-inflammatory agent, which enhances the body's ability to defend itself against viruses and that it is essential for the proper functioning of cells. In other words, vitamin C acts as an addition to our immune system. Vitamin C increases the number of white blood cells that fight the virus that causes the common cold. In the first three days after the onset of cold viruses multiply faster than the immune system is able to produce white blood cells, and therefore it is not doing its job. That is why the needed large doses of vitamin C to suppress viral infections, or viruses quickly deplete stores of vitamin C in the body.
The Food Supplement and Vitamin B9 (folic acid, folate)
Folic acid is a vitamin, which is contained in the grains, beer yeast, liver, and especially in spinach leaves. After absorption in the intestinal tract activated folic acid in the liver. The liver converts it into folinic acid, which is distributed to the various tissues of the body, or deposited in a reserve. Correct would be to say no folic acid and folate, all the more that there is a whole family of substances having the structure and biological activity similar to the activity of the classical vitamin B9. After absorption in the intestinal tract, these provitamins are converted into their simplest form, called folic acid itself.
Vitamin B9 is essential for human life, and many other organisms, such as simple bacteria. This substance, participating in the synthesis of nucleic acids, is really important for the growth and reproduction of the cells.
Vitamin E is a powerful antioxidant that protects our body cells from damage caused by free radicals. Free radicals are agents having high reactivity generated during normal metabolism, as well as exposure to environmental factors such as cigarette smoke or ultraviolet radiation. Vitamin E preserves fatty acids by the disintegration and compounds with other substances, which makes them hazardous to the body. Oxidation of fats leads to the formation of free radicals. Free radicals are extremely aggressive particles, which can cause extensive damage to the body – from cancer to the appearance of blood clots, and can damage DNA.
When present in the digestive tract of vitamin E, as a complex of vitamins and ascorbic acid are protected from oxidation. Fats and oils containing vitamin E are more resistant to rancidity than those in which it does not. Vitamin E is able to bind with oxygen and to prevent its conversion into toxic peroxides, and this provides a better supply of red blood cells with oxygen, which is then transferred from the blood to the heart and other organs. Vitamin E is not only an antioxidant, it also plays a very important role in generating energy.
Vitamin E plays an important role in all cellular respiration muscles, heart and skeletal features. In addition, it allows the muscles and nerves functioning under oxygen deficiency, thus increasing their ability to withstand stresses for a long time. It also causes dilation of blood vessels, allowing more blood flow to the heart. It is a kind of « antithrombin », which is very effectively working in the circulatory system, because it inhibits blood clotting, thereby preventing blood clots. It also contributes to the delivery of food to the cells, strengthens capillary walls and protects red blood cells from damage caused by poisons such as hydroperoxides (free radicals) present in the blood.
Vitamin E prevents oxidation of the hormones of the adrenal and pituitary gland and stimulates the perfect functioning of linoleic acid, which is an unsaturated fatty acid. Since the oxidation causes a cell aging, vitamin E slows the process. The fact that vitamin E is able to prolong the life has never been demonstrated, but believe that it can be installed.
Zinc is known for its protective properties in relation to the immune system against diseases. It helps the immune system by influencing the thymus (iron, which is present during the growth of the organism, but which atrophy in adulthood, and which is responsible for the generation of important cells of the immune system), and provides non-specific types of protection by retaining « integrity skin ». Zinc is useful for the prevention and treatment of respiratory infections because it stimulates the immune system.
was shown to reduce the duration of symptoms if kept cold in an average of 8 days, the presence of zinc using related disorders limited to 4-5 days, provided that its reception was initiated sooner, preferably in the range 24 hours after the onset of symptoms. Zinc facilitates the recovery of DNA damage, and increases the activity of the immune, vascular and hormonal systems. It is involved in the Krebs cycle and energy production. Recently, it has been found that zinc stop the progressive deterioration of vision in the elderly. It is also believed that it increases sexual power in men due to its ability to regulate testosterone in the prostate.
1. Adachi K, Nanba H, Otsuka M, Kuroda H. Blood pressure - lowering activity present in the fruit body of Grifola frondosa (maitake): I. Chem Pharm Bull 1988; 36:. 1000 - 1006
2. Adachi Y, Ohno N, Yadomae T. Activation of murine kupffer cells by administrationwith gel - forming (1 - - > 3) - beta - D - glucan from Grifola frondosa. Biol Pharm Bull 1998; 21:. 278 - 283
3. Adachi Y, Okazaki M, Ohno N, Yadomae T. Enhancement of cytokine production by macrophages stimulated
with (1 - - > 3) - beta - D - glucan, grifolan (GRN), isolated from Grifola frondosa. Biol Pharm Bull 1994; 17: 1554 - 1560. 4. Adachi K, Nanba H, Kuroda H. Potentiation of hostmediated antitumor activity in mice by beta - glucan obtained from Grifola frondosa (maitake). Chem Pharm Bull 1987; . 35: 262 - 270
5. Borchers AT, Stern JS, Hackman RM, et al. Mushrooms, tumors, and immunity. Proc Soc Exp Biol Med 1999; 221: 281 – 293.
6. Christens R, Schar D, Turner D. An evaluative study of the effectiveness of a strain of Grifola frondosa (maitake) against persistent vaginal Candida albicans proliferation (thrush). Unpublished; posted at planetbotanic. com/thrushtrial.htm.
7. Chichoke A. Maitake - the king of mushrooms. Townsend Lener for Doctors in 1994; 130:. 432 - 433
8. Fukushima M, Ohashi T, Fujiwara Y, Sonoyama K, Nakano M. Cholesterollowering effects of maitake (Grifola frondosa) fiber, shiitake (Lentinus edodes) fiber, and enokitake (Flammulina velutipes) fiber in rats. Exp Biol Med (Maywood) 2001 Sep; 226 (8):. 758 - 65
9. Hishida I, Nanba H, Kuroda H. Antitumor activity exhibited by oral administered extract from fruit body of Grifola frondosa (maitake). Chem Pharm Bull 1988; 36:. 1819 - 1827
10. Hobbs C. Grifola frondosa monograph. Santa Cruz, CA: Botanica Press; 1995:. 110 - 115
11. Horio H, Ohtsuru M. Maitake (Grifola frondosa) improve glucose tolerance of experimental diabetic rats. J Nutr Sci Vitaminol (Tokyo) 2001 Feb; 47 (1). 57 - 63
12. Jones K. Maitake: a potent medicinal food. Alt Comp Ther 1998; 4: 420 - 429.
13. Kabir Y, Kimura S. Dietary mushrooms reduce blood pressure in spontaneously hypertensive rats (SHR). J Nutr Sci Vitaminol 1989; . 35: 9194
14. Kabir Y, Hoshino T, Komai M, Kimura S. Histopathological changes in spontaneously hypertensive rats after feeding shiitake (Lentinus edodes) and maitake (Grifola frondosa) mushroom diets. J Clin Biochem Nutr 1989; 6:. 187 - 193.
15. Kabir Y, Yamaguchi M, Kimura S. Effect of shiitake (Lentinus edodes) and maitake (Grifola frondosa)
mushrooms on blood pressure and plasma lipids of spontaneously hypertensive rats. J Nutr Sci Vitaminol 1987; 33: 341 - 346.
16. Kubo K, Aoki H, Nanba H. Anti - diabetic activity present in the fruit body of Grifola frondosa (maitake) .I. Biol Pharm Bull 1994; 17:. 1106 - 1110
17. Kubo K, Nanba H. Antidiabetic mechanism of maitake (Grifola frondosa). In: Royse DJ, ed. Mushroom Biology and Mushroom Products. University Park, PA: Penn State University; 1996: 215 - 221.
18. Kubo K, Nanba H. The effect of maitake mushrooms on liver and serum lipids. Altern Ther Health Med 1996; 2: 62 - 66. Kubo K, Nanba H. Anti – hyperliposis effect of maitake fruit body (Grifola frondosa) .I. Biol Pharm Bull 1997; 20:. 781 - 785
19. Kurashige S, Akuzawa Y, Endo F. Effects of Lentinus edodes, Grifola frondosa and Pleurotus ostreatus administration on cancer outbreak, and activities of macrophages and lymphocytes in mice treated with a carcinogen, Nbutyl - N - butanolnitrosoamine. Immunopharmacol Immunotoxicol 1997 May; 19 (2). 175 - 83
20. Mizuno T, Zhuang C. Maitake, Grifola frondosa: pharmacological effects. Food Rev Int 1995; 11:. 135 - 149
21. Nanba H, Kubo K. Antitumor substance extracted from Grifola. U.S. Patent 5,854,404, issued December 29, 1998.
22. Nanba H. Antitumor activity of orally administered “ D - Fraction ” from maitake mushroom (Grifola frondosa). J Naturopathic Med 1993; 1:10 -. 15
23. Nanba H. Maitake D - fraction: healing and preventive potential for cancer. J Orthomol Med 1997; 12:43 -. 49
24. Nanba H, Kodama N, Schar D, Turner D. Effects of maitake (Grifola frondosa) glucan in HIV - infected patients. Mycoscience 2000; 41:. 293 - 295
25. Ohno N, Asada N, Adachi Y, Yadomae T. Enhancement of LPS triggered TNF - alpha (tumor necrosis factor - alpha) production by (1 - - > 3) - beta - Dglucans in mice. Biol Pharm Bull 1995; 18: 126 - 133.
26. Ohno N, Egawa Y, Hashimoto T, et al. Effect of betaglucans on the nitric oxide synthesis by peritoneal macrophage in mice. Biol Pharm Bull 1996; 19:. 608 - 612
27. Okamura M. Distribution of ascorbic acid analogs and associated glycosides in mushrooms. J Nutr Sci Vitaminol 1994; 40:81 -. 94
28.Suzuki I, Itani T, Ohno N, et al. Effect of a polysaccharide fraction from Grifola frondosa on immune response in mice. J Pharmacobiodyn 1985; 8:. 217 - 226
29. Suzuki I, Hashimoto K, Oikawa S, et al. Antitumor and immunomodulating activities of a beta - glucan obtained from liquid - cultured Grifola frondosa. Chem Pharm Bull 1989; 37:. 410 - 413
30. Takama F, Ninomiya S, Yoda R, et al. Parenchyma cells, chemical components of maitake mushroom (Grifola). Yamada Y, Nanba H, Kuroda H. Antitumor effect of orally administered extracts from fruit body of Grifola frondosa (maitake). Chemotherapy 1990; 38:. 790 - 796
31.Audera C et al. Mega - dose vitamin C in treatment of the common cold: a randomised controlled trial. 2001; 175 (7). 359 - 62
32. Douglas RM Vitamin C for preventing and treating the common cold. Cochrane Database of Systematic Reviews 2007; (3):. CD000980
33. Peterkofsky B. Ascorbate requirement for hydroxylation and secretion of procollagen: relationship to inhibition of collagen synthesis in scurvy. American Journal of Clinical Nutrition 1991; 54 (6 Suppl):. 1135 - 40
34. Fain Q. Musculoskeletal manifestations of scurvy. 2005; 72 (2):. 124 - 8
35. Fairfield KM et al. Vitamins for chronic diseases prevention in adults. Journal of the American Medical Association 2002; 287 (23): 3116 – 3126.
36. Li Y et al. New developments and novel therapeutic perspectives for vitamin C. Journal of Nutrition 2007; 137 (10): 2171 - 218437. Loria CM et al. Vitamin C status and morta lity in US adults. American Journal of Clinical Nutrition 2000; 72 (1): 139 – 145.
37. Knekt P et al. Antioxidant vitamins and coronary heart disease risk: a pooled analysis of 9 cohorts. American Journal of Clinical Nutrition 2004; 80 (6): 1508 – 20.
38. Joshipura KJ et al. The effect of fruit and vegetable intake on risk for coronary heart disease. Annals of Internal Medicine 2001; 134 (12): 1106 – 14
39. Chen Q et al. Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice. Proceeding of the National Academy of Sciences in 2008; 105 (32):. 11037 - 8
40. Traxer O. et al. Vitamin C and stone risk. Review of the literature. Progr è s en Urologie 2003; 13 (6): 1290 – 4
41. Urivetzky M et al. Ascorbic acid overdosing: a risk factor for calcium oxalate nephrolithiasis. Journal of Urology 1992; 147 (5):. 1215- 8
42. Serafini M et al. Effect of acute ingestion of fresh and stored lettuce (Lactuca sativa) on plasma total antioxidant capacity and antioxidant levels in human subjects. British Journal of Nutrition 2002; 88 (6). 615 - 23
43. Williams PG Vitamin retention in cook/chill and cook/hot - hold hospital food - services. 1996; 96 (5). 490 - 8
44. S.I.N.U. Societ à Italiana di Nutrizione Umana. Livelli di Assunzione.
45. Raccomandati di Energia e Nutrienti per la Popolazione Italiana. Revisione in 1996.
46. Klose P.K .: "Prove di efficacia degli estratti di echinacea", L'erborista, n.3, 1992
47. Giusti E .: "Echinacea, botanica, chimica, farmacologia, terapia", Erboristeria Domani, n. 11, 1992.
48. Grimm W. et al. A randomized controlled trial of the effect of fluid extract of Echinacea purpurea on the incidence and severity of colds and respiratory infections. Am. J. Med. 106, 138 - 143, 1999. Melchart D. et al. Echinacea root extracts for the prevention of upper respiratory tract infections: a double - blind, placebo - controlled randomized trial. Arch. Fam. Med. 7, 541 - 545, 1998